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Summary

The eficacy and safety of the association of aluminium hydroxide, acetylsalicilic acid, mepyramine maleate and caffeine (ENGOV) was evaluated in the treatment of the chronic headache /nausea and fatigue/myalgia after alcohool ingestion. Ninety- nine patients from 18 to 40 years old were divided into 4 groups according the posology indicated: A group: patients that ingested 1 tablet when in hang over and after 60 minutes of the ingestion didn´t take any tablets. Aa group: patients that ingested 1 tablet when in hang over and after 60 minutes, still having symptoms of headache/nausea and fatigue/myalgia, ingested 1 tablet. Ab group: patients that ingested 1 tablet when in hang over and after 60 minutes, still having symptoms of headache /nausea and fatigue/myalgia, ingested 2 tablets. Ac group: patients that ingested 1 tablet when in hang over and after 60 minutes, still having symptoms of headache /nausea and fatigue/myalgia, ingested 3 tablets of the medication. The results related to the safety of the medication showed excellent tolerability for all cases in all posology groups. No side effects were reported. All the information in this report showed us the excellent tolerability and efficacy of ENGOV in the relief of headache /nausea and fatigue/myalgia after alcohol ingestion.



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